Genetic architecture of body size in mammals

KE Kemper; PM Visscher; ME Goddard

Journal article

Genetic architecture of body size in mammals

KE Kemper, PM Visscher, ME Goddard

Genome Biology | Published : 2012

DOI: 10.1186/gb-2012-13-4-244

Abstract

Much of the heritability for human stature is caused by mutations of small-to-medium effect. This is because detrimental pleiotropy restricts large-effect mutations to very low frequencies. © 2012 BioMed Central Ltd.

University of Melbourne Researchers

Mike Goddard Author

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Grants

Awarded by National Institute of General Medical Sciences

Funding Acknowledgements

This research was supported under Australian Research Council's Discovery Projects funding scheme (project DP1093502). The views expressed herein are those of the authors and are not necessarily those of the Australian Research Council.